شیوع نفروپاتی دیابتیک در مازندران

Diabetic nephropathy is common in Mazandaran and a significant number of patients under chornic hemodialysis are diabetics. The present study was designed to study the prevalence and predisposing factors of diabetic nephropathy (DN) in Mazandaran. Methods: During a 20 months period from June 1993 through December 1994, 490 (350 female, 140 male) cases of non-insulin dependent diabetes mellitus (NIDDM) were diagnosed according to the criteria of National Diabetes Data Group. DN was diagnosed in 18 (11 male, 7 female) patients with proteinuria of 500 mg or more in a 24-hour urinary sample in at least two separate occasions, and excluding other causes of nephropathy. Results: 3.7 percent of all NIDDM patients had DN, 15+5 years after onset of diabetes. Male patients have higher prevalence of DN (7.8%) than female (2%). Onset of diabetes before 50 years age in male is a risk factor for DN (9.5%) as compared after 50 (4.5%) (P=0.01), in female the prevalence of DN before and after 50 is, 1 and 3.4 percent respectively (P=NS). Conclusions: In Mazandaran DN is not uncommon, it is more common in male patients than female. The age of onset, duration of diabetes and maleness are predisposing factors for DN.